Since publication of the third edition in 2004 there have been important advances. Several endocrine disorders, such as feline acromegaly and hyperaldosteronism, have risen in importance. The use of diet and novel insulins in diabetic cats, and new drugs such as trilostane and methimazole, which were briefly mentioned in previous editions are now considered routine. In addition, the genetic risks associated with many disorders have been elucidated.

 

• A new chapter presents the principles of interpreting endocrine test results and discusses how test performance is assessed in relation to diagnostic confidence.
• The central section on glands and their diseases is presented in a standard format -- detailing physiology, aetiology, clinical features, diagnosis and treatment - to aid information retrieval.
• The final section has been rewritten to focus on solving clinical and clinicopathological abnormalities with an endocrine dimension.

Introduction

Hormone assays and collection of samples

Principles of interpreting endocrine test results

The pituitary gland

Disorders of vasopressin production

Pituitary dwarfism

Acromegaly

The parathyroid gland

Hyperparathyroidism

Hypoparathyroidism

The thyroid gland: Canine hypothyroidism

Canine hyperthyroidism

Feline hyperthyroidism

Feline hypothyroidism

The pancreas

Canine diabetes mellitus

Feline diabetes mellitus

Insulinoma and other gastrointestinal tract tumours

The adrenal gland

Canine hypoadrenocorticism

Canine hyperadrenocorticism

Feline hyperadrenocorticism

Feline hypoadrenocorticism

Feline hyperaldosteronism

Presenting complaints and their investigation

Investigation of polyuria and polydipsia

Investigation of hypercalcaemia and hypocalcaemia

Investigation of unstable canine diabetes mellitus

Investigation of unstable feline diabetes mellitus

Ketoacidosis; Investigation of hypoglycaemia

Investigation of symmetrical

Carmel T. Mooney, MVB MPhil PhD DipECVIM-CA MRCVS
Carmel is a University College Dublin graduate who spent several years in Scotland where she completed both MPhil (The University of Edinburgh) and PhD (The University of Glasgow) theses on feline hyperthyroidism. Following this she returned to UCD where she is currently Senior Lecturer in Small Animal Internal Medicine. Carmel obtained the European Diploma in Veterinary Internal Medicine (Companion Animals) in 1998 and is also an RCVS Recognized Specialist in Small Animal Medicine (Endocrinology), awarded in recognition of her clinical and research work. She is a Past President of the BSAVA (2005-2006) and was founding Secretary of the European Society of Veterinary Endocrinology.

 

Mark E. Peterson, DVM DipACVIM
Mark graduated from the University of Minnesota in 1976, moved to NYC to do an internship and medical residency at The Animal Medical Center, and then completed a post-doctoral fellowship in endocrinology and nuclear medicine at The New York Hospital--Cornell Medical Center and the AMC, staying on there for over 30 years. In 2009 Mark opened the Animal Endocrine Clinic, a specialty referral hospital. Mark's clinical and research efforts have mainly been directed toward advancing the understanding of canine and feline endocrine disorders, especially diabetes mellitus and thyroid and adrenal disease. He has published more than 450 journal articles, book chapters and research abstracts, and is a frequent speaker at veterinary colleges and scientific seminars.